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Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia

BACKGROUND: Production of reactive oxygen species (ROS) and proinflammatory cytokines by microglial cells in response to viral brain infection contributes to both pathogen clearance and neuronal damage. In the present study, we examined the effect of herpes simplex virus (HSV)-1-induced, NADPH oxida...

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Détails bibliographiques
Auteurs principaux: Hu, Shuxian, Sheng, Wen S, Schachtele, Scott J, Lokensgard, James R
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192693/
https://ncbi.nlm.nih.gov/pubmed/21943001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-123
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