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Herpes simplex virus induces neural oxidative damage via microglial cell Toll-like receptor-2

BACKGROUND: Using a murine model of herpes simplex virus (HSV)-1 encephalitis, our laboratory has determined that induction of proinflammatory mediators in response to viral infection is largely mediated through a Toll-like receptor-2 (TLR2)-dependent mechanism. Published studies have shown that, li...

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Detalhes bibliográficos
Main Authors: Schachtele, Scott J, Hu, Shuxian, Little, Morgan R, Lokensgard, James R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904293/
https://ncbi.nlm.nih.gov/pubmed/20584314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-35
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