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Memory T-cells persisting in the brain following MCMV infection induce long-term microglial activation via interferon-γ

Murine cytomegalovirus (MCMV) brain infection stimulates microglial cell-driven proinflammatory chemokine production which precedes the presence of brain-infiltrating systemic immune cells. Here, we show that in response to MCMV brain infection, antigen-specific CD8(+) T-cells migrated into the brai...

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Detalhes bibliográficos
Main Authors: Mutnal, Manohar B., Hu, Shuxian, Little, Morgan R., Lokensgard, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204167/
https://ncbi.nlm.nih.gov/pubmed/21800103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-011-0042-5
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