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Memory T-cells persisting in the brain following MCMV infection induce long-term microglial activation via interferon-γ
Murine cytomegalovirus (MCMV) brain infection stimulates microglial cell-driven proinflammatory chemokine production which precedes the presence of brain-infiltrating systemic immune cells. Here, we show that in response to MCMV brain infection, antigen-specific CD8(+) T-cells migrated into the brai...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3204167/ https://ncbi.nlm.nih.gov/pubmed/21800103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-011-0042-5 |
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