Targeted high throughput sequencing in clinical cancer Settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity

BACKGROUND: Massively parallel sequencing technologies have brought an enormous increase in sequencing throughput. However, these technologies need to be further improved with regard to reproducibility and applicability to clinical samples and settings. METHODS: Using identification of genetic varia...

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Main Authors: Kerick, Martin, Isau, Melanie, Timmermann, Bernd, Sültmann, Holger, Herwig, Ralf, Krobitsch, Sylvia, Schaefer, Georg, Verdorfer, Irmgard, Bartsch, Georg, Klocker, Helmut, Lehrach, Hans, Schweiger, Michal R
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192667/
https://ncbi.nlm.nih.gov/pubmed/21958464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-4-68
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