Targeted high throughput sequencing in clinical cancer Settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity

BACKGROUND: Massively parallel sequencing technologies have brought an enormous increase in sequencing throughput. However, these technologies need to be further improved with regard to reproducibility and applicability to clinical samples and settings. METHODS: Using identification of genetic varia...

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Hlavní autoři: Kerick, Martin, Isau, Melanie, Timmermann, Bernd, Sültmann, Holger, Herwig, Ralf, Krobitsch, Sylvia, Schaefer, Georg, Verdorfer, Irmgard, Bartsch, Georg, Klocker, Helmut, Lehrach, Hans, Schweiger, Michal R
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192667/
https://ncbi.nlm.nih.gov/pubmed/21958464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-4-68
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