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Genome-Wide Massively Parallel Sequencing of Formaldehyde Fixed-Paraffin Embedded (FFPE) Tumor Tissues for Copy-Number- and Mutation-Analysis

BACKGROUND: Cancer re-sequencing programs rely on DNA isolated from fresh snap frozen tissues, the preparation of which is combined with additional preservation efforts. Tissue samples at pathology departments are routinely stored as formalin-fixed and paraffin-embedded (FFPE) samples and their use...

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Detalhes bibliográficos
Main Authors: Schweiger, Michal R., Kerick, Martin, Timmermann, Bernd, Albrecht, Marcus W., Borodina, Tatjana, Parkhomchuk, Dmitri, Zatloukal, Kurt, Lehrach, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678265/
https://ncbi.nlm.nih.gov/pubmed/19440246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005548
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