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Elevated Intact Proinsulin Levels Are Indicative of Beta-Cell Dysfunction, Insulin Resistance, and Cardiovascular Risk: Impact of the Antidiabetic Agent Pioglitazone

BACKGROUND: Insulin resistance (IR) and deterioration of beta-cell secretion are main features in the development of type 2 diabetes, which is reflected in increasing serum intact proinsulin levels in later disease stage. Introduction of stable assays that are able to distinguish between intact proi...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Pfützner, Andreas, Forst, Thomas
פורמט: Artigo
שפה:Inglês
יצא לאור: Diabetes Technology Society 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192645/
https://ncbi.nlm.nih.gov/pubmed/21722594
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