Stress-induced reinstatement of alcohol-seeking in rats is selectively suppressed by the neurokinin 1 (NK1) antagonist L822429

RATIONALE: Genetic inactivation or pharmacological antagonism of neurokinin 1 (NK1) receptors blocks morphine and alcohol reward in rodents, while NK1 antagonism decreases alcohol craving in humans. The role of the NK1 system for relapse-like behavior has not previously been examined. OBJECTIVE: Div...

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Main Authors: Schank, Jesse R., Pickens, Charles L., Rowe, Kelly E., Cheng, Kejun, Thorsell, Annika, Rice, Kenner C., Shaham, Yavin, Heilig, Markus
格式: Artigo
語言:Inglês
出版: 2011
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192232/
https://ncbi.nlm.nih.gov/pubmed/21340476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2201-z
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