Neurokinin-1 receptor antagonism attenuates neuronal activity triggered by stress-induced reinstatement of alcohol seeking

Substance P (SP) and its cognate neurokinin-1 receptor (NK1R) are involved in alcohol-related behaviors. We have previously reported that NK1R antagonism attenuates stress-induced reinstatement of alcohol seeking and suppresses escalated alcohol self-administration, but does not affect primary reinf...

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Veröffentlicht in:Neuropharmacology
Hauptverfasser: Schank, J.R., Nelson, B.S., Damadzic, R., Tapocik, J.D., Yao, M., King, C.E., Rowe, K.E., Cheng, K., Rice, K.C., Heilig, M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655129/
https://ncbi.nlm.nih.gov/pubmed/26188146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.07.009
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