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Immune Activation in the Female Genital Tract During HIV Infection Predicts Mucosal CD4 Depletion and HIV Shedding

Plasma viral load predicts genital tract human immunodeficiency virus (HIV) shedding in HIV-infected women. We investigated whether local mucosal T-cell activation (HLA-DR, CD38, CCR5, and Ki67) contributed to HIV shedding in the genital tracts of HIV-infected women. We showed that cervical cytobrus...

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Bibliographische Detailangaben
Hauptverfasser: Jaspan, Heather B., Liebenberg, Lenine, Hanekom, Willem, Burgers, Wendy, Coetzee, David, Williamson, Anna-Lise, Little, Francesca, Myer, Landon, Coombs, Robert W., Sodora, Don, Passmore, Jo-Ann
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192190/
https://ncbi.nlm.nih.gov/pubmed/21940422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir591
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