CD4 T Cell Depletion at the Cervix during HIV Infection Is Associated with Accumulation of Terminally Differentiated T Cells

In blood, the accumulation of terminally differentiated (TD) T cells during HIV infection is associated with CD4 T cell loss and HIV disease progression. Here, we investigated the maintenance and functional characteristics of memory T cells at the cervix. We found that CD4 T cell depletion at the ce...

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Detalhes bibliográficos
Main Authors: Gumbi, P. P., Jaumdally, S. Z., Salkinder, A. L., Burgers, W. A., Mkhize, N. N., Hanekom, W., Coetzee, D., Williamson, A., Passmore, J. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233181/
https://ncbi.nlm.nih.gov/pubmed/21994461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05671-11
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