Transgenic Expression of Entire Hepatitis B Virus in Mice Induces Hepatocarcinogenesis Independent of Chronic Liver Injury

Hepatocellular carcinoma (HCC), the third leading cause of cancer deaths worldwide, is most commonly caused by chronic hepatitis B virus (HBV) infection. However, whether HBV plays any direct role in carcinogenesis, other than indirectly causing chronic liver injury by inciting the host immune respo...

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Autors principals: Na, Bing, Huang, Zhiming, Wang, Qian, Qi, Zhongxia, Tian, Yongjun, Lu, Cheng-Chan, Yu, Jingwei, Hanes, Martha A., Kakar, Sanjay, Huang, Eric J., Ou, J.-H. James, Liu, Limin, Yen, T. S. Benedict
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192172/
https://ncbi.nlm.nih.gov/pubmed/22022578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026240
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