Transgenic expression of entire hepatitis B virus in mice induces hepatocarcinogenesis independent of chronic liver injury.

Hepatocellular carcinoma (HCC), the third leading cause of cancer deaths worldwide, is most commonly caused by chronic hepatitis B virus (HBV) infection. However, whether HBV plays any direct role in carcinogenesis, other than indirectly causing chronic liver injury by inciting the host immune respo...

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Main Authors: Bing Na, Zhiming Huang, Qian Wang, Zhongxia Qi, Yongjun Tian, Cheng-Chan Lu, Jingwei Yu, Martha A Hanes, Sanjay Kakar, Eric J Huang, J-H James Ou, Limin Liu, T S Benedict Yen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3192172?pdf=render
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