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Elucidation of the Glucose Transport Pathway in Glucose Transporter 4 via Steered Molecular Dynamics Simulations

BACKGROUND: GLUT4 is a predominant insulin regulated glucose transporter expressed in major glucose disposal tissues such as adipocytes and muscles. Under the unstimulated state, GLUT4 resides within intracellular vesicles. Various stimuli such as insulin translocate this protein to the plasma membr...

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Autori principali: Sheena, Aswathy, Mohan, Suma S., Haridas, Nidhina Pachakkil A., Anilkumar, Gopalakrishnapillai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192114/
https://ncbi.nlm.nih.gov/pubmed/22022441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025747
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