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Elucidation of the Glucose Transport Pathway in Glucose Transporter 4 via Steered Molecular Dynamics Simulations

BACKGROUND: GLUT4 is a predominant insulin regulated glucose transporter expressed in major glucose disposal tissues such as adipocytes and muscles. Under the unstimulated state, GLUT4 resides within intracellular vesicles. Various stimuli such as insulin translocate this protein to the plasma membr...

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Detalhes bibliográficos
Main Authors: Sheena, Aswathy, Mohan, Suma S., Haridas, Nidhina Pachakkil A., Anilkumar, Gopalakrishnapillai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192114/
https://ncbi.nlm.nih.gov/pubmed/22022441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025747
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