Neutrophil antimicrobial defense against Staphylococcus aureus is mediated by phagolysosomal but not extracellular trap-associated cathelicidin

Neutrophils kill invading pathogens by AMPs, including cathelicidins, ROS, and NETs. The human pathogen Staphylococcus aureus exhibits enhanced resistance to neutrophil AMPs, including the murine cathelicidin CRAMP, in part, as a result of alanylation of teichoic acids by the dlt operon. In this stu...

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Bibliographische Detailangaben
Hauptverfasser: Jann, Naja J., Schmaler, Mathias, Kristian, Sascha A., Radek, Katherine A., Gallo, Richard L., Nizet, Victor, Peschel, Andreas, Landmann, Regine
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Society for Leukocyte Biology 2009
Schlagworte:
Leukocytes: Tissue Interactions, Homeostasis and Host Defense
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192022/
https://ncbi.nlm.nih.gov/pubmed/19638500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0209053
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