Neutrophil antimicrobial defense against Staphylococcus aureus is mediated by phagolysosomal but not extracellular trap-associated cathelicidin

Neutrophils kill invading pathogens by AMPs, including cathelicidins, ROS, and NETs. The human pathogen Staphylococcus aureus exhibits enhanced resistance to neutrophil AMPs, including the murine cathelicidin CRAMP, in part, as a result of alanylation of teichoic acids by the dlt operon. In this stu...

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Detalhes bibliográficos
Main Authors: Jann, Naja J., Schmaler, Mathias, Kristian, Sascha A., Radek, Katherine A., Gallo, Richard L., Nizet, Victor, Peschel, Andreas, Landmann, Regine
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2009
Assuntos:
Leukocytes: Tissue Interactions, Homeostasis and Host Defense
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192022/
https://ncbi.nlm.nih.gov/pubmed/19638500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0209053
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