Beta-Lactamase Repressor BlaI Modulates Staphylococcus aureus Cathelicidin Antimicrobial Peptide Resistance and Virulence

BlaI is a repressor of BlaZ, the beta-lactamase responsible for penicillin resistance in Staphylococcus aureus. Through screening a transposon library in S. aureus Newman for susceptibility to cathelicidin antimicrobial peptide, we discovered BlaI as a novel cathelicidin resistance factor. Additiona...

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Publicat a:PLoS One
Autors principals: Pence, Morgan A., Haste, Nina M., Meharena, Hiruy S., Olson, Joshua, Gallo, Richard L., Nizet, Victor, Kristian, Sascha A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549145/
https://ncbi.nlm.nih.gov/pubmed/26305782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136605
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