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Requirements for Skp1 processing by cytosolic prolyl 4(trans)-hydroxylase and α-N-acetylglucosaminyltransferase enzymes involved in O(2)-signaling in Dictyostelium
The social amoeba Dictyostelium expresses a hypoxia inducible factor-α (HIFα)-type prolyl 4-hydroxylase (P4H1) and an α-N-acetylglucosaminyltransferase (Gnt1) that sequentially modify proline-143 of Skp1, a subunit of the SCF (Skp1/Cullin/F-box protein)-class of E3 ubiquitin-ligases. Prior genetic s...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3192012/ https://ncbi.nlm.nih.gov/pubmed/21247092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101977w |
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