Requirements for Skp1 processing by cytosolic prolyl 4(trans)-hydroxylase and α-N-acetylglucosaminyltransferase enzymes involved in O(2)-signaling in Dictyostelium

The social amoeba Dictyostelium expresses a hypoxia inducible factor-α (HIFα)-type prolyl 4-hydroxylase (P4H1) and an α-N-acetylglucosaminyltransferase (Gnt1) that sequentially modify proline-143 of Skp1, a subunit of the SCF (Skp1/Cullin/F-box protein)-class of E3 ubiquitin-ligases. Prior genetic s...

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Bibliographische Detailangaben
Hauptverfasser: van der Wel, Hanke, Johnson, Jennifer M., Xu, Yuechi, Karunaratne, Chamini V., Wilson, Kyle D., Vohra, Yusuf, Boons, Geert-Jan, Taylor, Carol M., Bendiak, Brad, West, Christopher M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192012/
https://ncbi.nlm.nih.gov/pubmed/21247092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101977w
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