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Contemporary paradigms for cholinergic ligand design guided by biological structure
The identification of the various nicotinic receptor subtypes, when coupled with the recent development of three-dimensional structures of surrogate extracellular receptor domains, offers new opportunities to design nicotinic ligands. Conformation and fluctuations in receptor structure are critical...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3191913/ https://ncbi.nlm.nih.gov/pubmed/15050619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2003.10.072 |
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