Rab38 targets to lamellar bodies and normalizes their sizes in lung alveolar type II epithelial cells

Rab38 is a rat Hermansky-Pudlak syndrome gene that plays an important role in surfactant homeostasis in alveolar type II (ATII) pneumocytes. We examined Rab38 function in regulating lamellar body (LB) morphology in ATII cells. Quantitative electron microscopy revealed that LBs in ATII cells were ∼77...

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Main Authors: Zhang, Linghui, Yu, Kevin, Robert, Kyle W., DeBolt, Kristine M., Hong, Nankang, Tao, Jian-Qin, Fukuda, Mitsunori, Fisher, Aron B., Huang, Shaohui
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191760/
https://ncbi.nlm.nih.gov/pubmed/21764986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00056.2011
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