Rab38 targets to lamellar bodies and normalizes their sizes in lung alveolar type II epithelial cells

Rab38 is a rat Hermansky-Pudlak syndrome gene that plays an important role in surfactant homeostasis in alveolar type II (ATII) pneumocytes. We examined Rab38 function in regulating lamellar body (LB) morphology in ATII cells. Quantitative electron microscopy revealed that LBs in ATII cells were ∼77...

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Huvudupphovsmän: Zhang, Linghui, Yu, Kevin, Robert, Kyle W., DeBolt, Kristine M., Hong, Nankang, Tao, Jian-Qin, Fukuda, Mitsunori, Fisher, Aron B., Huang, Shaohui
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2011
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191760/
https://ncbi.nlm.nih.gov/pubmed/21764986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00056.2011
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