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Hyper-phosphorylation of mouse cardiac titin contributes to Transverse Aortic Constriction induced diastolic dysfunction

RATIONALE: Mechanisms underlying diastolic dysfunction need to be better understood. OBJECTIVE: To study the role of titin in diastolic dysfunction using a mouse model of experimental heart failure induced by transverse aortic constriction (TAC). METHODS AND RESULTS: Eight weeks post-TAC surgery mic...

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Detalhes bibliográficos
Main Authors: Hudson, Bryan, Hidalgo, Carlos, Saripalli, Chandra, Granzier, Henk
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191198/
https://ncbi.nlm.nih.gov/pubmed/21835910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.246819
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