PCBP2 Enhances the Antiviral Activity of IFN-α against HCV by Stabilizing the mRNA of STAT1 and STAT2

Interferon-α (IFN-α) is a natural choice for the treatment of hepatitis C, but half of the chronically infected individuals do not achieve sustained clearance of hepatitis C virus (HCV) during treatment with IFN-α alone. The virus can impair IFN-α signaling and cellular factors that have an effect o...

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Bibliografiske detaljer
Main Authors: Xin, Zhongshuai, Han, Wei, Zhao, Zhiqiang, Xia, Qing, Yin, Bin, Yuan, Jiangang, Peng, Xiaozhong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191149/
https://ncbi.nlm.nih.gov/pubmed/22022391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025419
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