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Diastolic dysfunction is associated with cardiac fibrosis in the senescence-accelerated mouse

Diastolic heart failure is a major cause of mortality in the elderly population. It is often preceded by diastolic dysfunction, which is characterized by impaired active relaxation and increased stiffness. We tested the hypothesis that senescence-prone (SAMP8) mice would develop diastolic dysfunctio...

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Detalhes bibliográficos
Main Authors: Reed, Alana L., Tanaka, Atsuko, Sorescu, Dan, Liu, Hong, Jeong, Euy-Myoung, Sturdy, Megan, Walp, Erik R., Dudley, Samuel C., Sutliff, Roy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191096/
https://ncbi.nlm.nih.gov/pubmed/21724869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00407.2010
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