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Diastolic dysfunction is associated with cardiac fibrosis in the senescence-accelerated mouse

Diastolic heart failure is a major cause of mortality in the elderly population. It is often preceded by diastolic dysfunction, which is characterized by impaired active relaxation and increased stiffness. We tested the hypothesis that senescence-prone (SAMP8) mice would develop diastolic dysfunctio...

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Autores principales: Reed, Alana L., Tanaka, Atsuko, Sorescu, Dan, Liu, Hong, Jeong, Euy-Myoung, Sturdy, Megan, Walp, Erik R., Dudley, Samuel C., Sutliff, Roy L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191096/
https://ncbi.nlm.nih.gov/pubmed/21724869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00407.2010
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