Diastolic dysfunction is associated with cardiac fibrosis in the senescence-accelerated mouse

Diastolic heart failure is a major cause of mortality in the elderly population. It is often preceded by diastolic dysfunction, which is characterized by impaired active relaxation and increased stiffness. We tested the hypothesis that senescence-prone (SAMP8) mice would develop diastolic dysfunctio...

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Autori principali: Reed, Alana L., Tanaka, Atsuko, Sorescu, Dan, Liu, Hong, Jeong, Euy-Myoung, Sturdy, Megan, Walp, Erik R., Dudley, Samuel C., Sutliff, Roy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
Soggetti:
Muscle Mechanics and Ventricular Function
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191096/
https://ncbi.nlm.nih.gov/pubmed/21724869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00407.2010
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