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Galectin-3 Protein Modulates Cell Surface Expression and Activation of Vascular Endothelial Growth Factor Receptor 2 in Human Endothelial Cells

Angiogenesis is heavily influenced by VEGF-A and its family of receptors, particularly VEGF receptor 2 (VEGF-R2). Like most cell surface proteins, VEGF-R2 is glycosylated, although the function of VEGF-R2 with respect to its glycosylation pattern is poorly characterized. Galectin-3, a glycan binding...

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Detalhes bibliográficos
Main Authors: Markowska, Anna I., Jefferies, Kevin C., Panjwani, Noorjahan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191032/
https://ncbi.nlm.nih.gov/pubmed/21715322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.226423
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