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Ubiquitin Ligase Activity of Cul3-KLHL7 Protein Is Attenuated by Autosomal Dominant Retinitis Pigmentosa Causative Mutation

Substrate-specific protein degradation mediated by the ubiquitin proteasome system (UPS) is crucial for the proper function of the cell. Proteins are specifically recognized and ubiquitinated by the ubiquitin ligases (E3s) and are then degraded by the proteasome. BTB proteins act as the substrate re...

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Detalles Bibliográficos
Main Authors: Kigoshi, Yu, Tsuruta, Fuminori, Chiba, Tomoki
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190939/
https://ncbi.nlm.nih.gov/pubmed/21828050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.245126
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