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Ubiquitin Ligase Activity of Cul3-KLHL7 Protein Is Attenuated by Autosomal Dominant Retinitis Pigmentosa Causative Mutation

Substrate-specific protein degradation mediated by the ubiquitin proteasome system (UPS) is crucial for the proper function of the cell. Proteins are specifically recognized and ubiquitinated by the ubiquitin ligases (E3s) and are then degraded by the proteasome. BTB proteins act as the substrate re...

詳細記述

保存先:
書誌詳細
主要な著者: Kigoshi, Yu, Tsuruta, Fuminori, Chiba, Tomoki
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190939/
https://ncbi.nlm.nih.gov/pubmed/21828050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.245126
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