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Enhanced Autophagy from Chronic Toxicity of Iron and Mutant A53T α-Synuclein: IMPLICATIONS FOR NEURONAL CELL DEATH IN PARKINSON DISEASE
Parkinson disease (PD), a prevalent neurodegenerative motor disorder, is characterized by the rather selective loss of dopaminergic neurons and the presence of α-synuclein-enriched Lewy body inclusions in the substantia nigra of the midbrain. Although the etiology of PD remains incompletely understo...
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| Główni autorzy: | , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Biochemistry and Molecular Biology
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190914/ https://ncbi.nlm.nih.gov/pubmed/21795716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.268409 |
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