Transgenic Mice Overexpressing the Divalent Metal Transporter 1 Exhibit Iron Accumulation and Enhanced Parkin Expression in the Brain

Exposure to divalent metals such as iron and manganese is thought to increase the risk for Parkinson’s disease (PD). Under normal circumstances, cellular iron and manganese uptake is regulated by the divalent metal transporter 1 (DMT1). Accordingly, alterations in DMT1 levels may underlie the abnorm...

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Опубликовано в: :Neuromolecular Med
Главные авторы: Zhang, Cheng-Wu, Tai, Yee Kit, Chai, Bing-Han, Chew, Katherine C. M., Ang, Eng-Tat, Tsang, Fai, Tan, Bryce W. Q., Hong, Eugenia T. E., Asad, Abu Bakar Ali, Chuang, Kai-Hsiang, Lim, Kah-Leong, Soong, Tuck Wah
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2017
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Original Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570798/
https://ncbi.nlm.nih.gov/pubmed/28695462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12017-017-8451-0
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