Transgenic Mice Overexpressing the Divalent Metal Transporter 1 Exhibit Iron Accumulation and Enhanced Parkin Expression in the Brain

Exposure to divalent metals such as iron and manganese is thought to increase the risk for Parkinson’s disease (PD). Under normal circumstances, cellular iron and manganese uptake is regulated by the divalent metal transporter 1 (DMT1). Accordingly, alterations in DMT1 levels may underlie the abnorm...

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Detalhes bibliográficos
Publicado no:Neuromolecular Med
Main Authors: Zhang, Cheng-Wu, Tai, Yee Kit, Chai, Bing-Han, Chew, Katherine C. M., Ang, Eng-Tat, Tsang, Fai, Tan, Bryce W. Q., Hong, Eugenia T. E., Asad, Abu Bakar Ali, Chuang, Kai-Hsiang, Lim, Kah-Leong, Soong, Tuck Wah
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570798/
https://ncbi.nlm.nih.gov/pubmed/28695462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12017-017-8451-0
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