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Protein Phosphatase 2A (B55α) Prevents Premature Activation of Forkhead Transcription Factor FoxM1 by Antagonizing Cyclin A/Cyclin-dependent Kinase-mediated Phosphorylation

The forkhead transcription factor FoxM1 controls expression of a large number of genes that are specifically expressed during the G(2) phase of the cell cycle. Throughout most of the cell cycle, FoxM1 activity is restrained by an autoinhibitory mechanism, involving a repressor domain present in the...

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書誌詳細
主要な著者: Alvarez-Fernández, Mónica, Halim, Vincentius A., Aprelia, Melinda, Mohammed, Shabaz, Medema, René H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190881/
https://ncbi.nlm.nih.gov/pubmed/21813648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253724
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