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Protein Phosphatase 2A (B55α) Prevents Premature Activation of Forkhead Transcription Factor FoxM1 by Antagonizing Cyclin A/Cyclin-dependent Kinase-mediated Phosphorylation
The forkhead transcription factor FoxM1 controls expression of a large number of genes that are specifically expressed during the G(2) phase of the cell cycle. Throughout most of the cell cycle, FoxM1 activity is restrained by an autoinhibitory mechanism, involving a repressor domain present in the...
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主要な著者: | , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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American Society for Biochemistry and Molecular Biology
2011
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190881/ https://ncbi.nlm.nih.gov/pubmed/21813648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253724 |
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