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Truncation of Murine Ca(v)1.2 at Asp-1904 Results in Heart Failure after Birth
The carboxyl-terminal intracellular tail of the l-type Ca(2+) channel Ca(V)1.2 modulates various aspects of channel activity. For example, deletion of the carboxyl-terminal sequence at Ser-1905 increased Ca(V)1.2 currents in an expression model. To verify this finding in an animal model, we inserted...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190806/ https://ncbi.nlm.nih.gov/pubmed/21832054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.252312 |
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