Solution Structure of Tandem SH2 Domains from Spt6 Protein and Their Binding to the Phosphorylated RNA Polymerase II C-terminal Domain

Spt6 is a highly conserved transcription elongation factor and histone chaperone. It binds directly to the RNA polymerase II C-terminal domain (RNAPII CTD) through its C-terminal region that recognizes RNAPII CTD phosphorylation. In this study, we determined the solution structure of the C-terminal...

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Detalhes bibliográficos
Main Authors: Liu, Jianping, Zhang, Jiahai, Gong, Qingguo, Xiong, Peng, Huang, Hongda, Wu, Bo, Lu, Guowei, Wu, Jihui, Shi, Yunyu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190728/
https://ncbi.nlm.nih.gov/pubmed/21676864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.252130
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