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Homeodomain-interacting Protein Kinase-2 Stabilizes p27(kip1) by Its Phosphorylation at Serine 10 and Contributes to Cell Motility

HIPK2 is a serine/threonine kinase that acts as a coregulator of an increasing number of factors involved in cell survival and proliferation during development and in response to different types of stress. Here we report on a novel target of HIPK2, the cyclin-dependent kinase inhibitor p27(kip1). HI...

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Main Authors: Pierantoni, Giovanna Maria, Esposito, Francesco, Tornincasa, Mara, Rinaldo, Cinzia, Viglietto, Giuseppe, Soddu, Silvia, Fusco, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190708/
https://ncbi.nlm.nih.gov/pubmed/21715331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230854
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