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Studies on Human DNA Polymerase ϵ and GINS Complex and Their Role in DNA Replication
In eukaryotic cells, DNA replication is carried out by the coordinated action of three DNA polymerases (Pols), Pol α, δ, and ϵ. In this report, we describe the reconstitution of the human four-subunit Pol ϵ and characterization of its catalytic properties in comparison with Pol α and Pol δ. Human Po...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190704/ https://ncbi.nlm.nih.gov/pubmed/21705323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.256289 |
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