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Autocatalytic Cleavage of Human γ-Glutamyl Transpeptidase Is Highly Dependent on N-Glycosylation at Asparagine 95
γ-Glutamyl transpeptidase (GGT) is a heterodimeric membrane enzyme that catalyzes the cleavage of extracellular glutathione and other γ-glutamyl-containing compounds. GGT is synthesized as a single polypeptide (propeptide) that undergoes autocatalytic cleavage, which results in the formation of the...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190695/ https://ncbi.nlm.nih.gov/pubmed/21712391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.248823 |
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