Activity-dependent Phosphorylation of Neuronal Kv2.1 Potassium Channels by CDK5

Dynamic modulation of ion channel expression, localization, and/or function drives plasticity in intrinsic neuronal excitability. Voltage-gated Kv2.1 potassium channels are constitutively maintained in a highly phosphorylated state in neurons. Increased neuronal activity triggers rapid calcineurin-d...

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Bibliographic Details
Main Authors: Cerda, Oscar, Trimmer, James S.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Neurobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190682/
https://ncbi.nlm.nih.gov/pubmed/21712386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.251942
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