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Regulation of intrinsic excitability in hippocampal neurons by activity-dependent modulation of the Kv2.1 potassium channel

Kv2.1 is the prominent somatodendritic sustained or delayed rectifier voltage-gated potassium (Kv) channel in mammalian central neurons, and is a target for activity-dependent modulation via calcineurin-dependent dephosphorylation. Using hanatoxin-mediated block of Kv2.1 we show that, in cultured ra...

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Bibliographic Details
Main Authors: Mohapatra, Durga P., Misonou, Hiroaki, Pan, Sheng-Jun, Held, Joshua E., Surmeier, D. James, Trimmer, James S.
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743964/
https://ncbi.nlm.nih.gov/pubmed/19276663
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