Calcium- and Metabolic State-Dependent Modulation of the Voltage-Dependent Kv2.1 Channel Regulates Neuronal Excitability in Response to Ischemia

Ischemic stroke is often accompanied by neuronal hyperexcitability (i.e., seizures), which aggravates brain damage. Therefore, suppressing stroke-induced hyperexcitability and associated excitoxicity is a major focus of treatment for ischemic insults. Both ATP-dependent and Ca(2+)-activated K(+) cha...

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Vydáno v:J Neurosci
Hlavní autoři: Misonou, Hiroaki, Mohapatra, Durga P., Menegola, Milena, Trimmer, James S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2005
Témata:
Neurobiology of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725654/
https://ncbi.nlm.nih.gov/pubmed/16319318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3370-05.2005
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