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Synthesis and Antitumor Molecular Mechanism of Agents Based on Amino 2-(3′,4′,5′-Trimethoxybenzoyl)-benzo[b]furan: Inhibition of Tubulin and Induction of Apoptosis

Induction of apoptosis is a promising strategy that could lead to the discovery of new molecules active in cancer chemotherapy. This property is generally observed when cells are treated with agents that target microtubules, dynamic structures that play a crucial role in cell division. Small molecul...

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Detalles Bibliográficos
Autores principales: Romagnoli, Romeo, Baraldi, Pier Giovanni, Lopez-Cara, Carlota, Cruz-Lopez, Olga, Carrion, Maria Dora, Salvador, Maria Kimatrai, Bermejo, Jaime, Estévez, Sara, Estévez, Francisco, Balzarini, Jan, Brancale, Andrea, Ricci, Antonio, Chen, Longchuan, Kim, Jae Gwan, Hamel, Ernest
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190670/
https://ncbi.nlm.nih.gov/pubmed/21805646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201100279
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