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A tight coupling between β(2)Y97 and β(2)F200 of the GABA(A) receptor mediates GABA binding
The GABA(A) receptor is an oligopentameric chloride channel that is activated via conformation changes induced upon the binding of the endogenous ligand, GABA, to the extracellular inter-subunit interfaces. While dozens of amino acid residues at the α/β interface have been implicated in ligand bindi...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190653/ https://ncbi.nlm.nih.gov/pubmed/21806616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07409.x |
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