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A State-Dependent Salt-Bridge Interaction Exists across the β/α Intersubunit Interface of the GABA(A) Receptor

The GABA(A) receptor is a multisubunit protein that transduces the binding of a neurotransmitter at an intersubunit interface into the opening of a central ion channel. The structural components that mediate the steps involved in this action are poorly defined. A large amount of work has focused on...

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Autors principals: Laha, Kurt T., Wagner, David A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063723/
https://ncbi.nlm.nih.gov/pubmed/21209255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.068619
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