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A tight coupling between β(2)Y97 and β(2)F200 of the GABA(A) receptor mediates GABA binding

The GABA(A) receptor is an oligopentameric chloride channel that is activated via conformation changes induced upon the binding of the endogenous ligand, GABA, to the extracellular inter-subunit interfaces. While dozens of amino acid residues at the α/β interface have been implicated in ligand bindi...

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Bibliografische gegevens
Hoofdauteurs: Tran, Phu N., Laha, Kurt T., Wagner, David A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190653/
https://ncbi.nlm.nih.gov/pubmed/21806616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07409.x
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