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Synthetic Fab Fragments that Bind the HIV-1 gp41 Heptad Repeat Regions

Recent work has demonstrated that antibody phage display libraries containing restricted diversity in the complementarity determining regions (CDRs) can be used to target a wide variety of antigens with high affinity and specificity. In the most extreme case, antibodies whose combining sites are com...

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Autors principals: Liu, Yanyun, Regula, Lauren K., Stewart, Alex, Lai, Jonathan R.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190029/
https://ncbi.nlm.nih.gov/pubmed/21925149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.09.012
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