The Rad50 Coiled Coil Domain is indispensable for Mre11 complex functions

The Mre11 complex (Mre11, Rad50, Xrs2 in S. cerevisiae) influences diverse functions in the DNA damage response. The complex comprises the globular DNA binding domain and the Rad50 hook domain which are linked by a long and extended Rad50 coiled coil domain. In this study, rad50 alleles encoding tru...

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Bibliographic Details
Main Authors: Hohl, Marcel, Kwon, Youngho, Galván, Sandra Muñoz, Xue, Xiaoyu, Tous, Cristina, Aguilera, Andrés, Sung, Patrick, Petrini, John H.J.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190017/
https://ncbi.nlm.nih.gov/pubmed/21892167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2116
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