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The Rad50 Coiled Coil Domain is indispensable for Mre11 complex functions
The Mre11 complex (Mre11, Rad50, Xrs2 in S. cerevisiae) influences diverse functions in the DNA damage response. The complex comprises the globular DNA binding domain and the Rad50 hook domain which are linked by a long and extended Rad50 coiled coil domain. In this study, rad50 alleles encoding tru...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190017/ https://ncbi.nlm.nih.gov/pubmed/21892167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2116 |
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