Allosteric modulation of Ca(2+) channels by G proteins, voltage-dependent facilitation, protein kinase C, and Ca(v)β subunits
N-type and P/Q-type Ca(2+) channels are inhibited by neurotransmitters acting through G protein-coupled receptors in a membrane-delimited pathway involving Gβγ subunits. Inhibition is caused by a shift from an easily activated “willing” (W) state to a more-difficult-to-activate “reluctant” (R) state...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11296298/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051628998 |
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