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Evidence for transient requirement of the IgH enhancer.

A transcriptional enhancer is thought to play a major role in determining tissue-specific expression of the immunoglobulin heavy chain (IgH) gene (1-3). However in three B-lymphoid cell lines the Ig enhancer has been lost due to a spontaneous deletion, yet heavy chain synthesis persists at a high le...

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Detalles Bibliográficos
Autores principales: Klein, S, Gerster, T, Picard, D, Radbruch, A, Schaffner, W
Formato: Artigo
Lenguaje:Inglês
Publicado: 1985
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC318960/
https://ncbi.nlm.nih.gov/pubmed/3936022
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