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Quantitation of protein–protein interactions by thermal stability shift analysis

Thermal stability shift analysis is a powerful method for examining binding interactions in proteins. We demonstrate that under certain circumstances, protein–protein interactions can be quantitated by monitoring shifts in thermal stability using thermodynamic models and data analysis methods presen...

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Detalhes bibliográficos
Main Authors: Layton, Curtis J, Hellinga, Homme W
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189529/
https://ncbi.nlm.nih.gov/pubmed/21674662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.674
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